Avana 50 mg works by inhibiting the enzyme PDE5 (phosphodiesterase type 5), which is responsible for breaking down cyclic GMP in the smooth muscle of the penis. By blocking this enzyme, Avanafil helps increase the levels of cyclic GMP, resulting in the relaxation of the blood vessels in the penis. This leads to improved blood flow, which helps men achieve and sustain an erection when sexually stimulated.

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