Forum

MDM2 PROTAC

Proteolysis-targeting chimera (PROTAC) is a hetero-bifunctional molecule that contains a ligand for recruiting an E3 ligase, a linker, and another ligand to bind with the target protein for degradation. Murine double minute 2 (MDM2), as a commonly used E3 ligase, has been utilized successfully for small molecule PROTAC. Creative Biolabs has been a long-term expert in the field of PROTAC development, and we can provide a variety of ligand screening strategies for PROTAC projects. MDM2 PROTAC https://www.creative-biolabs.com/protac/ligand-screening-for-mdm2-based-protac.htm

Reply to this topic Share on my timeline

0 Replies

No replies to show